variant-effect

Here are 4 public repositories matching this topic...

robert-mcdermott / MaveScape

A desktop workbench for multiplexed assays of variant effect (MAVEs) and deep mutational scanning: count tables to scores with uncertainty, QC, variant-effect maps, structures, calibration and reproducible records. One program, no install of Python or R; MaveDB import and export.

bioinformatics reproducible-research protein-structure computational-biology dms reproducibility functional-genomics deep-mutational-scanning protein-engineering variant-interpretation mave mavedb saturation-mutagenesis variant-effect

Updated Oct 13, 2026
JavaScript

amurlaniakea / variant-confidence

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Calibrated confidence layer for variant-effect pathogenicity (AlphaMissense/ESM-1v/EVE)

python bioinformatics calibration pathogenicity ece cli-tool conformal-prediction agpl-3-0 variant-effect

Updated Jul 18, 2026
Python

RenX86 / AlphaVX

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CLI tool that batch-scores VCF variants against AlphaGenome and generates interpretable multi-modal effect reports.

cli bioinformatics genomics vcf deepmind vcftools bioinformatics-tool bioinformatics-software alphagenome variant-effect

Updated Sep 21, 2026
Python

berntpopp / mavedb-link

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MCP server for MaveDB: quantitative variant-effect scores from Multiplexed Assays of Variant Effect (MAVE) and deep mutational scanning — functional evidence as typed tools for LLM agents.

bioinformatics mcp functional-genomics deep-mutational-scanning claude variant-interpretation mavedb llm-tools model-context-protocol mcp-server fastmcp variant-effect genefoundry

Updated Oct 12, 2026
Python

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